| 9/2/2017 | Kentucky | 24 | at | Southern Miss (8-5) | 17 | at CUSA | ||
| 9/9/2017 | Eastern Kentucky (4-7) | 16 | at | Kentucky | 27 | OVC (1AA) | ||
| 9/16/2017 | Kentucky | 23 | at | South Carolina (9-4,5-3) | 13 | |||
| 9/23/2017 | Florida (4-7,3-5) | 28 | at | Kentucky | 27 | |||
| 9/30/2017 | Eastern Michigan (5-7) | 20 | at | Kentucky | 24 | MAC | ||
| 10/7/2017 | Missouri (7-6,4-4) | 34 | at | Kentucky | 40 | |||
| 10/21/2017 | Kentucky | 7 | at | Mississippi State (9-4,4-4) | 45 | |||
| 10/28/2017 | Tennessee (4-8,0-8) | 26 | at | Kentucky | 29 | |||
| 11/4/2017 | Mississippi (6-6,3-5) | 37 | at | Kentucky | 34 | |||
| 11/11/2017 | Kentucky | 44 | at | Vanderbilt (5-7,1-7) | 21 | |||
| 11/18/2017 | Kentucky | 13 | at | Georgia (13-2,8-2) | 42 | |||
| 11/25/2017 | Louisville (8-5) | 44 | at | Kentucky | 17 | ACC | ||
| 12/29/2017 | Kentucky | 23 | vs | Northwestern (10-3) | 24 | Music City Bowl (Nashville TN) | vs B10 |
| vs Kentucky | vs Other Opponents | Kentucky compared to OOs | |
| Record: | 6-7 | 86-64 | |
| Points Scored: | 28.23 | 28.99 | 0.76 |
| Points Allowed: | 25.54 | 25.44 | 0.10 |
| Margin: | 2.69 | 3.55 | 0.86 |
| Total Points: | 53.77 | 54.43 | -0.66 |